Problem: The ArcMap.exe.config or the Miner.Responder.Explorer.exe.config file is not pointing to the Responder business servers (DataServices.exe, PredictionServices.exe).

Fix: Edit both configuration files on the client machine to ensure they are pointed at the Responder business servers:

• ArcGIS\Bin\ArcMap.exe.config

• ArcGIS\Bin\Responder\Miner.Responder.Explorer.exe.config

In both configuration files:

1. Scroll to the bottom of the file and look for the following:

   <channel ref="msmq" isServer="false" ComputerName="." />
   

2. In the ComputerName attribute value, enter the name of the machine that is hosting the Responder business servers.